When and where
21st – 27th of August, 2011, Ljubljana
Who should attend:
People from industry engaged in downstream processing, graduate student and postdocs who want to increase their theoretical and practical knowledge of modern downstream processing
Participants will receive:
- Extensive overview of the current state of the art in downstream processing of biomacromolecules.
- Theoretical aspects of commonly applied techniques including chromatography, precipitation, liquid-liquid extraction, ultrafiltration, and crystallization. Special topic will be scale-up of each technique.
- Features of specific groups of biomacromolecules including antibodies, plasmid DNA, and viruses
- Modern in-process analytics
- Downstream process design based on collected results
- Confronting opinions of participants, experts from industry and academia as well as equipment manufacturers
- day: introduction to the course concept, lectures about downstream processing state-of-the-art, current challenges and theory of unit operations
- day: lectures about specificity of each molecule type (viruses, plasmids, proteins); hands-on work
- day: lecture about process analytical technology (PAT) and in-process control (IPC), hands-on work
- day: hands-on work, analysis of the results and report preparation
- day: results presentation, workshop on design of an optimal purification process for each type of molecules based on experimental data; lecture about further development of downstream processing, conclusion of the workshop